Brain perfusion imaging in neonates

Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral imaging play an important role diagnostic therapeutic decision-making. To identify at-risk situations, must accurately evaluate both regional global perfusion. date, assessment remains challenging. The available modalities such as magnetic resonance (MRI), ultrasound imaging, computed tomography (CT), near-infrared spectroscopy or nuclear have multiple compromises limitations. Several promising methods are being developed to achieve better accuracy higher robustness, particular using advanced MRI techniques. objective this state-of-the-art review is analyze methodology challenges describe currently modalities, outline future perspectives.